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Your Guide to Genetics & Nutrition

Listed below are the top genes that can be influenced by lifestyle and nutrition.

GeneNormal FunctionSNP IDMajor AlleleMinor Allele
MTRR MTRR is an enzyme which helps maintain methionine synthase function, a key component of the methionine cycle.A66G a g
MUC1 Muc1 protein forms part of the protective mucus layer which lines our lungs and digestive system.C/G66A a g
NAF1 NAF1 is a key component of the telomerase enzyme.n/a g a
NOD2 NOD2 plays an important role in the immune system.C2104T c t
G30491C/T g c
NOS3 NOS3 is an enzyme responsible for synthesizing nitric oxide, which is important in many biological processes, especially cardiac function.G51-898A a g
T894G g t
A-52+1009T t a
NQO1 NQO1 is an enzyme with an antioxidant role.C559T c t
PCSK9 The PCSK9 protein controls the number of low-density lipoprotein (LDL) receptors on the surface of cells. LDL receptors are critical for regulating blood cholesterol levels. The PCSK9 protein waylays LDL receptors after they transport cholesterol into cells, leading to their destruction. This prevents LDL receptors being recirculated back to the cell surface, which means fewer receptors overall and more cholesterol remaining in the bloodstream.E670G a g
V474I a g
R46L g t
L253F c t
G1327A g a
C2037A c a
PEMT PEMT is an enzyme which generates phosphatidylcholine, a key component of cell membranes.G523A g a
PPARG PPARG is a receptor protein mainly expressed in adipose tissue that regulates glucose metabolsim.
68777C>G c g
SHMT1 SHMT1 is an enzyme of the one carbon cycle, converting folate into a variety of other cellular products.C1420T c t
SLC19A1 SLC19A1 is a folate transporter.A80G g a
SLC2A14 SLC2A14 is a transporter protein which shuttles glucose into cells.A8025266G a g
C8008132A c a
C8023530T c t
SOD2 SOD2 is an antioxidant enzyme found specifically in the mitochondria of cells.T47C, A16V c t
SOD3 SOD3 is an antioxidant enzyme which is secreted by cells in the brain, lungs and other tissues at high risk of oxidative damage.C691G c g
SULT1A1 SULT1A1 is an enzyme which targets hormones, neurotransmitters for degradation.G638A c t
TCF7L2 TCF7L2 is a transcription factor which regulates a wide variety of cellular processes including synthesis of glucagon in the pancreas.
53341C>T c t
TERT TERT forms part of the telomerase enzyme which is responsible for maintaining chromosome telomeres in selected cells.G1574-3777T g t
TRPM6 TRPM6 is a channel protein which traffics magnesium into cells in the kidney.A33+2944G a g
VDR VDR is the receptor for vitamin D, its main function is to regulate calcium uptake from the gut into the bloodstream.BsmI g a
FokI c t
TaqI t c
ApaI t g
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