Your Guide to Genetics & Nutrition

Listed below are the top genes that can be influenced by lifestyle and nutrition.

GeneNormal FunctionSNP IDMajor AlleleMinor Allele
GCLM GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione.C-590T c t
GPX1 GPX1 is a peroxidase enzyme which plays a key antioxidant role.C599T c t
GPX4 GPX4 is a peroxidase enzyme which plays a key antioxidant role.T660C c t
GRIA3 GRIA3 is a glutamate receptor important in neuronal signaling.A17114C a c
G11395A g a
GSTP1 GSTP1 is an enzyme which assists the antioxidant glutathione remove harmful reactive oxygen species.A313G a g
HNMT HNMT breaks down the molecule histamine which is important in the immune response.C314T c t
IL10 IL-10 is an anti-inflammatory cytokine which acts to damp down the immune systems inflammatory response.A-1117G a g
IL6 IL-6 is a signaling molecule which transmits signals between cells, especially those of the immune system.C-237G, C-174G g c
IL8 IL-8 is a signalling molecule, used to transmit messages between cells and tissues in the body.A-352T a t
LDLR LDLR is a receptor protein which specifically recognises LDL particles.G67+2015T g t
MAOA MAOA is an enzyme involved in the processing of neurotransmitters, it is sometimes called the "warrior" gene due to proposed links with aggression.T1410C c t
G1052+680C g c
G891T t g
C306+527T t c
MAOB MAOB is an enzyme involved in the processing of neurotransmitters, it's importance relative to MAOA is under debate.A1348-36G a g
MAT1A MAT1A is an enzyme responsible for the formation of SAM, a methyl donor molecule key in many other biological processes.G791A g a
MTHFD1 MTHFD1 is an enzyme is an enzyme involved in the conversion of dietary folate into a variety of key products.G1958A g a
MTHFR MTHFR is an involved in the conversion of dietary folate into a variety of key products.C667T c t
C117T c t
A1298C a c
MTNR1B MTNR1B is a receptor for melatonin, one of the key sleep hormones.C2120T c t
MTR MTR is responsible for the regeneration of methionine from homocysteine. 
2756A>G a g
MTRR MTRR is an enzyme which helps maintain methionine synthase function, a key component of the methionine cycle.A66G a g
MUC1 Muc1 protein forms part of the protective mucus layer which lines our lungs and digestive system.C/G66A a g
NAF1 NAF1 is a key component of the telomerase enzyme.n/a g a
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