Your Guide to Genetics & Nutrition
Representing over 500 hours of research, the Gene Food Guide to Nutrigenomics was built to catalogue genetic markers that can be influenced by nutrition. Before building the personalized nutrition algorithm we now offer to consumers and health systems, our research team, led by geneticist Dr. Aaron Gardner compiled an exhaustive list of the scientific research in the field of nutrigenomics. Applicable genes were scored based on the state of the scientific evidence with a Science Grade and published, with citations, in the guide. Genes that had sufficient evidence were included in our algorithm and weighted based on strength of research. The guide is updated regularly as new research emerges.
Genes
79
SNPs
150+
Citations
400+
| Gene | Normal Function | SNP ID | Major Allele | Minor Allele | |
|---|---|---|---|---|---|
| G6PD | G6PD is an enzyme which produces NADPH, key in the biosysnthesis of many molecules and in oxidative defense. | A466G | a | g | |
| G292A | g | a | |||
| GAD1 | GAD1 is an enzyme which catalyzes the formation of the important neurotransmitter GABA. | G638+315C | g | c | |
| C170814316A | c | a | |||
| GC | GC is a protein which binds to vitamin D allowing for its efficient transport around the body. | A26-796C | t | c | |
| GCKR |
GCKR is a protein produced in the liver which regulates glucose metabolism. |
26532T>C | c | a | |
| GCLC | GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione. | C53410037T | c | t | |
| GCLM | GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione. | C-590T | c | t | |
| GPX1 | GPX1 is a peroxidase enzyme which plays a key antioxidant role. | C599T | c | t | |
| GPX4 | GPX4 is a peroxidase enzyme which plays a key antioxidant role. | T660C | c | t | |
| GRIA3 | GRIA3 is a glutamate receptor important in neuronal signaling. | A17114C | a | c | |
| G11395A | g | a | |||
| GSTP1 | GSTP1 is an enzyme which assists the antioxidant glutathione remove harmful reactive oxygen species. | A313G | a | g | |
| HNMT | HNMT breaks down the molecule histamine which is important in the immune response. | C314T | c | t | |
| IL10 | IL-10 is an anti-inflammatory cytokine which acts to damp down the immune systems inflammatory response. | A-1117G | a | g | |
| IL23R | IL23R is the receptor for the protein IL-23, which is involved in the immune response. | G533A | g | a | |
| IL6 | IL-6 is a signaling molecule which transmits signals between cells, especially those of the immune system. | C-237G, C-174G | g | c | |
| IL8 | IL-8 is a signalling molecule, used to transmit messages between cells and tissues in the body. | A-352T | a | t | |
| KIAA1109 | This protein produced by this gene is believed to play a role in guiding the growth and differentiation of epithelial cells and also in the onset of tumors. | a | g | ||
| LDLR | LDLR is a receptor protein which specifically recognises LDL particles. | G67+2015T | g | t | |
| LPA |
LPA is one of the major lipoproteins found in our body, responsible for cholesterol transport. |
19986711A>G | t | c | |
| 82290T>C | a | g | |||
| Ile1891Met | t | c | |||
| LPL |
LPL is an enzyme which regulates triglycerides in lipoproteins, and their uptake by cells. Situated on the surface of capillary cells, this enzyme plays a crucial role in the breakdown and assimilation of dietary fat. |
19986711A>G | a | g | |
| MADD | MADD is thought to regulate controlled cell death but is also implicated in other cellular events. | 47336320A>T | a | t |