Your Guide to Genetics & Nutrition

Representing over 500 hours of research, the Gene Food Guide to Nutrigenomics was built to catalogue genetic markers that can be influenced by nutrition. Before building the personalized nutrition algorithm we now offer to consumers and health systems, our research team, led by geneticist Dr. Aaron Gardner compiled an exhaustive list of the scientific research in the field of nutrigenomics. Applicable genes were scored based on the state of the scientific evidence with a Science Grade and published, with citations, in the guide. Genes that had sufficient evidence were included in our algorithm and weighted based on strength of research. The guide is updated regularly as new research emerges.

Genes

SNPs

150+

Citations

400+

Gene	Normal Function	SNP ID	Major Allele	Minor Allele
GCLC	GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione.	C53410037T	c	t
GCLM	GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione.	C-590T	c	t
GPX1	GPX1 is a peroxidase enzyme which plays a key antioxidant role.	C599T	c	t
GPX4	GPX4 is a peroxidase enzyme which plays a key antioxidant role.	T660C	c	t
GRIA3	GRIA3 is a glutamate receptor important in neuronal signaling.	A17114C	a	c
GRIA3		G11395A	g	a
GSTP1	GSTP1 is an enzyme which assists the antioxidant glutathione remove harmful reactive oxygen species.	A313G	a	g
HNMT	HNMT breaks down the molecule histamine which is important in the immune response.	C314T	c	t
IL10	IL-10 is an anti-inflammatory cytokine which acts to damp down the immune systems inflammatory response.	A-1117G	a	g
IL23R	IL23R is the receptor for the protein IL-23, which is involved in the immune response.	G533A	g	a
IL6	IL-6 is a signaling molecule which transmits signals between cells, especially those of the immune system.	C-237G, C-174G	g	c
IL8	IL-8 is a signalling molecule, used to transmit messages between cells and tissues in the body.	A-352T	a	t
LDLR	LDLR is a receptor protein which specifically recognises LDL particles.	G67+2015T	g	t
MADD	MADD is thought to regulate controlled cell death but is also implicated in other cellular events.	47336320A>T	a	t
MAOA	MAOA is an enzyme involved in the processing of neurotransmitters, it is sometimes called the "warrior" gene due to proposed links with aggression.	T1410C	c	t
		G1052+680C	g	c
		G891T	t	g
		C306+527T	t	c
MAOB	MAOB is an enzyme involved in the processing of neurotransmitters, it's importance relative to MAOA is under debate.	A1348-36G	a	g
MAT1A	MAT1A is an enzyme responsible for the formation of SAM, a methyl donor molecule key in many other biological processes.	G791A	g	a
MTHFD1	MTHFD1 is an enzyme is an enzyme involved in the conversion of dietary folate into a variety of key products.	G1958A	g	a
MTHFR	MTHFR is an involved in the conversion of dietary folate into a variety of key products.	C667T	c	t
		C117T	c	t
		A1298C	a	c
MTNR1B	MTNR1B is a receptor for melatonin, one of the key sleep hormones.	C2120T	c	t
MTR	MTR is responsible for the regeneration of methionine from homocysteine.	2756A>G	a	g

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