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Brain & Mental Health

Genes that play a role in cognitive performance and mental health.

Heart Health

PCSK9

The PCSK9 protein controls the number of low-density lipoprotein (LDL) receptors on the surface of cells. LDL receptors are critical for regulating blood cholesterol levels. The PCSK9 protein waylays LDL receptors after they transport cholesterol into cells, leading to their destruction. This prevents LDL receptors being recirculated back to the cell surface, which means fewer receptors overall and more cholesterol remaining in the bloodstream.
Heart Health

DHCR7

The DHCR7 gene encodes the enzyme 7-dehydrocholesterol reductase, which is essential for the production of cholesterol.
Brain & Mental Health

DRD2

DRD2 is the major dopamine receptor in the brain.
Brain & Mental Health

DOCK7

DOCK7 is a protein which is important in the formation and maintenance of neurons.
Brain & Mental Health

COMT

COMT is an enzyme which inactivates important neurotransmitters such as dopamine and epinephrine.
Brain & Mental Health

AKT1

AKT1 is an enzyme which is responsible for ensuring the survival of neurons.
Brain & Mental Health

MAOA

MAOA is an enzyme involved in the processing of neurotransmitters, it is sometimes called the "warrior" gene due to proposed links with aggression.
Brain & Mental Health

MAOB

MAOB is an enzyme involved in the processing of neurotransmitters, it's importance relative to MAOA is under debate.
Longevity

CYP24A1

CYP24A1 is an enzyme which converts the active form of vitamin D3 into an inactive form.
Heart Health

MTHFR

MTHFR is an involved in the conversion of dietary folate into a variety of key products.
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