Your Guide to Genetics & Nutrition

Representing over 500 hours of research, the Gene Food Guide to Nutrigenomics was built to catalogue genetic markers that can be influenced by nutrition. Before building the personalized nutrition algorithm we now offer to consumers and health systems, our research team, led by geneticist Dr. Aaron Gardner compiled an exhaustive list of the scientific research in the field of nutrigenomics. Applicable genes were scored based on the state of the scientific evidence with a Science Grade and published, with citations, in the guide. Genes that had sufficient evidence were included in our algorithm and weighted based on strength of research. The guide is updated regularly as new research emerges.

Genes

90+

SNPs

170+

Citations

500+

Gene	Normal Function	SNP ID	Major Allele	Minor Allele
G6PD	G6PD is an enzyme which produces NADPH, key in the biosysnthesis of many molecules and in oxidative defense.	A466G	a	g
G6PD		G292A	g	a
GAD1	GAD1 is an enzyme which catalyzes the formation of the important neurotransmitter GABA.	G638+315C	g	c
GAD1		C170814316A	c	a
GC	GC is a protein which binds to vitamin D allowing for its efficient transport around the body.	A26-796C	t	c
GCKR	GCKR is a protein produced in the liver which regulates glucose metabolism.	26532T>C	c	a
GCLC	GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione.	C53410037T	c	t
GCLM	GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione.	C-590T	c	t
GJB2	Connexin 26 is involved in the transport of potassium ions and other small molecules between adjacent cells.	A20216312G	a	g
GPX1	GPX1 is a peroxidase enzyme which plays a key antioxidant role.	C599T	c	t
GRIA3	GRIA3 is a glutamate receptor important in neuronal signaling.	A17114C	a	c
GRIA3		G11395A	g	a
GSTP1	GSTP1 is an enzyme which assists the antioxidant glutathione remove harmful reactive oxygen species.	A313G	a	g
HMGCR	An enzyme in the biochemical pathway that produces cholesterol.	T75360714C	t	c
HNMT	HNMT breaks down the molecule histamine which is important in the immune response.	C314T	c	t
IL10	IL-10 is an anti-inflammatory cytokine which acts to damp down the immune systems inflammatory response.	A-1117G	a	g
IL23R	IL23R is the receptor for the protein IL-23, which is involved in the immune response.	G533A	g	a
IL6	IL-6 is a signaling molecule which transmits signals between cells, especially those of the immune system.	C-237G, C-174G	g	c
IL8	IL-8 is a signalling molecule, used to transmit messages between cells and tissues in the body.	A-352T	a	t
KIAA1109	This protein produced by this gene is believed to play a role in guiding the growth and differentiation of epithelial cells and also in the onset of tumors.		a	g
LDLR	LDLR is a receptor protein which specifically recognises LDL particles.	G67+2015T	g	t
LPA	LPA is one of the major lipoproteins found in our body, responsible for cholesterol transport.	19986711A>G	t	c
		82290T>C	a	g
		Ile1891Met	t	c
LPL	LPL is an enzyme which regulates triglycerides in lipoproteins, and their uptake by cells. Situated on the surface of capillary cells, this enzyme plays a crucial role in the breakdown and assimilation of dietary fat.	19986711A>G	a	g