|rsID Number||Major Allele||Minor Allele||Minor Allele Frequency (%)|
The SNP rs780094 in the GCKR gene is associated with an increased risk of type-2 diabetes and also alterations to the lipid profile depending on which allele is present. The ‘A’ allele is associated with elevated levels of circulating triglycerides whereas the ‘G’ allele is associated with an increased risk of type-2 diabetes, with alterations in insulin levels detected in the blood. In both instances, the mechanism behind the susceptibility is not well understood3-5.
|Low GI diet|
Due to the dual nature of rs780094 exact dietary advice is hard to provide, however in both instances moving away from high-GI foods to more complex low-GI equivalents would prove beneficial.
Discuss this information with your doctor before taking any course of action.