Heart Health Genes - Page 2 Dr. Gina Leisching Heart Health GenesNOS3NOS3 is an enzyme responsible for synthesizing nitric oxide, which is important in many biological processes, especially cardiac function. Heart Health GenesF8F8 is an essential blood clotting protein. Gastrointestinal GenesCBSCBS is an enzyme which converts homocysteine into cystathionine, the first step of the transsulfuration pathway. Heart Health GenesACYP2ACYP2 is an enzyme which controls the movement of ions across the cell membrane, specifically muscle cells. Heart Health GenesACEACE is an enzyme which converts the inactive protein angiotensin I into the active angiotensin II, which is key in regulating blood pressure. Gastrointestinal GenesABCG8ABCG8 is a transporter protein, controlling the absorption and excretion of cholesterol and other lipids in the gut. Heart Health GenesSHMT1SHMT1 is an enzyme of the one carbon cycle, converting folate into a variety of other cellular products. Heart Health GenesMTHFRMTHFR is an involved in the conversion of dietary folate into a variety of key products. « 1 2