The SNP T61803311C or rs174547 is associated with altered lipid profiles with the ‘C’ allele being associated with reduced LDL cholesterol levels in individuals on a diet low in unsaturated fats 5. This correlated with an earlier study which showed that the largest effects related to this SNP were observed in those with a low unsaturated fat intake 6.
However, it is unclear what, if any, health effects are associated with this SNP as it remains unclear how exactly saturated and unsaturated fats impact health, as such it is not currently possible to provide specific nutrient guidelines.
|Observe lipid intake|
It remains unclear how exactly saturated and unsaturated fat intake and the SNP T61803311C or rs174547 interact. As this area of research is under constant our understating is likely to improve rapidly. Therefore, while no current nutrient advice can be provided, it is worthwhile considering your lipid intake, and keeping this polymorphism in mind for later study.
Discuss this information with your doctor before taking any course of action.