|Minor Allele Frequency (%)
The risk ‘G’ allele of T40844G has been associated with alterations in the blood cholesterol and lipid profile of individuals 5. Given its vital role for neuronal development it is not clear how this SNP can alter lipid profiles. One hypothesis is that lipids which are usually required to maintain the protective coating of neuronal cells are instead released into the blood.
Additionally, although lipid profiles are altered no health impacts have been associated with this SNP.
Discuss this information with your doctor before taking any course of action.