A-F - Page 3 Dr. Gina Leisching Gastrointestinal GenesARG1ARG1 is an enzyme which forms part of the urea cycle, clearing the body of harmful ammonia based products. Immune System GenesAOC1AOC1 is an enzyme that breaks down histamine and other related compounds. Brain & Mental Health GenesAKT1AKT1 is an enzyme which is responsible for ensuring the survival of neurons. Endocrine GenesADIPOQAdipoQ is expressed solely in fat tissue and is important in controlling fat metabolism. Heart Health GenesACYP2ACYP2 is an enzyme which controls the movement of ions across the cell membrane, specifically muscle cells. Heart Health GenesACEACE is an enzyme which converts the inactive protein angiotensin I into the active angiotensin II, which is key in regulating blood pressure. Gastrointestinal GenesABCG8ABCG8 is a transporter protein, controlling the absorption and excretion of cholesterol and other lipids in the gut. Longevity GenesABCA1ABCA1 acts as a cholesterol pump, removing cholesterol from the interior of the cell. Longevity GenesCYP24A1CYP24A1 is an enzyme which converts the active form of vitamin D3 into an inactive form. Musculoskeletal GenesCYP2R1CYP2R1 is an enzyme expressed in the liver that converts dietary vitamin D into a form which can be transported around the body. Sleep GenesADORA2AADORA2A is a receptor for adenosine; adenosine binds and promotes the induction of sleep. Sleep GenesADAADA is responsible for breaking down the sleep promoting adenosine, thus promoting wakefulness. « 1 2 3
