Lab Tests

Seven genes linked to high homocysteine levels and what to do about them

Homocysteine is a vital molecule required for numerous processes within the cells of our body to ensure good health. However, as with much in life, sometimes you can have too much of a good thing. When present at elevated levels homocysteine is associated with numerous poor health outcomes including; increased cardiovascular risk (R,R), increased risk… Read More

Cystic fibrosis, nutrition and choline

We’re going to have a bit of  change of tack with topics and rather than talk about how polymorphisms can affect otherwise healthy people; I’ll instead talk about how polymorphisms can impact on people with already existing diseases. This also gives me a chance to talk about the research that initially got me interested in… Read More

Don’t fear the fridge! Histamine intolerance is bigger than food

Updated September 4th, 2017  Histamine intolerance. A real condition with a very unfortunate name. No one is actually histamine intolerant, we all need histamine, it’s an essential neurotransmitter. (R) However, as with anything else, too much of a good thing can cause problems. When we accumulate more histamine than our body can handle, symptoms begin,… Read More

Can you handle a high protein diet? The answer may be genetic

Updated October 15th, 2017 Just like I think it’s fair to say that New York City is a “drinking town,” I think it’s also fair to say that America is a “protein country.” We are all obsessed with protein, and lucky for us, there is an ample cheap supply produced by our factory farming machine…. Read More

Dealing with Lipoprotein(a): tests, supplements, strategy

Updated September 19th, 2017 Lipoprotein(a), also called Lp(a), has gotten a good deal of press lately as a metric to watch if you’re concerned with heart health. Elevated Lp(a) levels have been linked with an increased risk of cardiovascular disease, and unlike some other cardio related biomarkers, they’re reputed to be tough to move with… Read More

The Warrior Gene: 5 common myths debunked

Much has been written about the so called “warrior gene” MAOA, also sometimes not as diplomatically referred to as the Psycho gene. We all carry this gene but certain mutations in these genes have been linked to an increased risk of violence, especially when there has been early life abuse [R]. First made famous by… Read More

The science of MTHFR mutations explained

Updated April 28th, 2017 If you’re interested in personalized genetic medicine you will have undoubtedly come across the protein methylenetetrahydrofolate reductase (MTHFR). MTHFR is an enzyme which is encoded by the MTHFR gene and functions to convert 5,10-methylenetetrahydrofolate (MeTHF) to 5-methlytetrahydrofolate (MTHF). What sounds like a pretty un-inspiring reaction has actually become one of, if… Read More

Are transglutaminase 2 IgG antibodies evidence of gluten sensitivity or full blown celiac?

Most people believe the world of gluten can be broken down into two groups: celiac, and everyone else. However, the functional medicine community would add a third group: those who are “gluten sensitive.” But what does this mean? Are there lab tests that prove gluten sensitivity, but fall short of full blown celiac disease? Where… Read More

Do I have an MTHFR mutation? Here’s how to find out

Updated August 2nd, 2017  Summary: Everyone has an MTHFR gene in one form or another. An MTHFR “mutation” usually means you inherited a type of the gene associated with a decreased ability to metabolize folic acid and folate. I some cases, people with MTHFR mutations benefit from supplementing with methylfolate, which is the “bioactive” form of… Read More

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